Efektivitas Klinis Akupunktur dalam Mengurangi Nyeri Kepala Sindrom Liver Fire: Studi Kasus

Dewi Jeni, Amal Prihatono, Chantika Mahadini

Abstract


Cephalgia, encompassing migraine and tension-type headache (TTH), is a major global health burden characterized by high disability rates. The limitations of conventional pharmacotherapy, including the risk of medication-overuse headache (MOH) and potential organ toxicity, highlight the urgent need for safer and more sustainable complementary approaches. Traditional Chinese Medicine (TCM) offers a holistic solution through the concept of Bian Zheng Lun Zhi (syndrome differentiation), particularly for Liver Fire syndrome frequently associated with high-intensity chronic headaches. This research is a clinical case study on one 42-year-old female patient diagnosed with migraine without aura and TTH exhibiting Liver Fire manifestations, aiming to evaluate the clinical efficacy of a standardized six-point acupuncture protocol (LR3, GB20, LI4, EX-HN5, GB34, and SP6). The intervention consisted of twelve sessions over six weeks. Results demonstrated significant clinical improvement, with Visual Analog Scale (VAS) scores decreasing from 8 to 0 and the absence of pain attacks at the end of the therapy period. Furthermore, objective TCM parameters indicated a restoration of physiological balance. These findings confirm that acupuncture effectively alleviates cephalgia by targeting the underlying pathology of Liver Fire syndrome through therapeutic mechanisms involving the down-regulation of neurogenic inflammation (CGRP, SP), restoration of mitochondrial function, and modulation of the autonomic nervous system

Full Text:

PDF

References


Chen Y, et al. Global trends and regional disparities in the burden of headache disorders, 1990–2021: a comprehensive analysis of the global burden of disease study. The Journal of Headache and Pain. 2023;24(1).

Stovner LJ, Hagen K, Linde M, Steiner TJ. The global prevalence of headache: an update, with analysis of the influences of methodological factors on prevalence estimates. The Journal of Headache and Pain. 2022;23(1):34.

Sudharta H, Barus JFA, Suswanti I. Comorbidities, Social, and Psychological Factors Associated with Headache in Adult Indonesians: Data from the 5th Indonesian Family Life Survey (IFLS-5). Universa Medicina. 2024.

American Academy of Family Physicians. Headache: Diagnosis and Management. American Family Physician. 2022.

Ropper AH, Samuels MA, Klein JP, Prasad S. Adams and Victor's Principles of Neurology. 11th ed. New York: McGraw-Hill Education; 2019.

Diener HC, Dodick D, Evers S, et al. Pathophysiology, prevention, and treatment of medication overuse headache. The Lancet Neurology. 2019;18(9):891-902.

Linde K, Allais G, Brinkhaus B, et al. Acupuncture for the prevention of episodic migraine. Cochrane Database of Systematic Reviews. 2016;(6).

Kelly RB, Willis J. Acupuncture for Pain. American Family Physician. 2019;100(2):89-96.

Maciocia G. The Practice of Chinese Medicine: The Treatment of Diseases with Acupuncture and Chinese Herbs. 3rd ed. Elsevier; 2021.

Zhang Y, Li J, Wang Y, Chen X. Restoring brain health: Electroacupuncture at GB20 and LR3 for migraine mitigation through mitochondrial restoration via PINK1/Parkin signaling pathway. Journal of Pain Research. 2024;17:2345–2358.

Zhou M, Pang F, Liao D, et al. Electroacupuncture at Fengchi (GB20) and Yanglingquan (GB34) ameliorates paralgesia through microglia-mediated neuroinflammation in a rat model of migraine. Brain Sciences. 2023;13(4):541.

Zhang X, et al. Efficacy of Acupuncture-Related Therapy for Migraine: A Systematic Review and Network Meta-Analysis. Journal of Pain Research. 2024;17:1107–1132.

Deadman P, Al-Khafaji M, Baker K. A Manual of Acupuncture. 2nd ed. Hove: Journal of Chinese Medicine Publications; 2007.

Yin RK. Case Study Research and Applications: Design and Methods. 6th ed. Thousand Oaks, CA: Sage Publications; 2018.

Hawker GA, Mian S, Kendzerska T, French M. Measures of adult pain: Visual Analog Scale for Pain (VAS Pain), Numeric Rating Scale for Pain (NRS Pain), McGill Pain Questionnaire (MPQ), and Short-Form McGill Pain Questionnaire (SF-MPQ). Arthritis Care & Research. 2011;63(S11):S240-S252.

MacPherson H, Altman DG, Hammerschlag R, et al. Revised STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA): extending the CONSORT statement. PLoS Medicine. 2010;7(6):e1000261.

World Health Organization. WHO Standard Acupuncture Point Locations in the Western Pacific Region. Manila: WHO Regional Office for the Western Pacific; 2008.

Li C, et al. Mechanism of acupuncture intervention in migraine without aura based on magnetic resonance spectroscopy imaging. Journal of Liaoning University of Traditional Chinese Medicine. 2023;27:119–124.

Zhao ZQ. Neural mechanism underlying acupuncture analgesia. Progress in Neurobiology. 2008;85(4):355-375.

Lu Y, Sun Z, Huang P, Wang Y. Effect of acupuncture combined with auricular bean embedding on autonomic nervous system function, heart rate variability and mental state of migraine patients. American Journal of Translational Research. 2024;16(10):6148-6158




DOI: https://doi.org/10.52643/jbik.v16i2.7943

Refbacks

  • There are currently no refbacks.


Copyright (c) 2026 Jurnal Bidang Ilmu Kesehatan

Flag Counter